L-histidyl-L-leucine
(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoic acid
Molecular Identity
L-histidyl-L-leucine
(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoic acid
PubChem CID: 189008
His-Leu is a dipeptide formed from L-histidine and L-leucine residues. It has a role as a metabolite. It is a tautomer of a His-Leu zwitterion.
2D Structure
Properties
C12H20N4O3
Molecular Formula
268.31
Molecular Weight
g/mol
268.1535
Exact Mass
Da
-2.2
XLogP
Drug-like (Lipinski: < 5)
121
TPSA
Good oral absorption (< 140 A²)
4
H-Bond Donors
5
H-Bond Acceptors
322
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)CC(C(=O)O)NC(=O)C(CC1=CN=CN1)NIsomeric SMILES
SMILES: CC(C)C[C@@H](C(=O)O)NC(=O)[C@H](CC1=CN=CN1)NSynonyms(20)
7763-65-7HistidylleucineL-histidyl-L-leucineN-L-Histidyl-L-leucine(2S)-2-[[(2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoic acid(2S)-2-[[(2S)-2-Azaniumyl-3-(1H-imidazol-5-yl)propanoyl]amino]-4-methylpentanoate(2S)-2-(((2S)-2-amino-3-(1H-imidazol-5-yl)propanoyl)amino)-4-methylpentanoic acid(2S)-2-(((2S)-2-azaniumyl-3-(1H-imidazol-5-yl)propanoyl)amino)-4-methylpentanoateRefChem:924415H-HIS-LEU-OHHis-leuhistidyl-leucine(S)-2-((S)-2-Amino-3-(1H-imidazol-4-yl)propanamido)-4-methylpentanoic acidL-Leucine, L-histidyl-HL dipeptide
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to L-histidyl-L-leucine
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