Ofirnoflast
1-[4-(4-amino-7-cyclopropylpyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-3-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]urea
Molecular Identity
Ofirnoflast
1-[4-(4-amino-7-cyclopropylpyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-3-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]urea
PubChem CID: 162365111
2D Structure
Properties
C23H19F4N7O2
Molecular Formula
501.40
Molecular Weight
g/mol
501.1536
Exact Mass
Da
3.5
XLogP
Drug-like (Lipinski: < 5)
124
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
10
H-Bond Acceptors
842
Complexity
SMILES
Canonical SMILES
SMILES: C1CC1N2C=C(C3=C(N=CN=C32)N)C4=CC(=C(C=C4)NC(=O)NC5=NOC(=C5)C6(CC6)C(F)(F)F)FIsomeric SMILES
SMILES: C1CC1N2C=C(C3=C(N=CN=C32)N)C4=CC(=C(C=C4)NC(=O)NC5=NOC(=C5)C6(CC6)C(F)(F)F)FSynonyms(20)
ofirnoflast2731294-23-654PY2PBN7S1-[4-(4-amino-7-cyclopropylpyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl]-3-[5-[1-(trifluoromethyl)cyclopropyl]-1,2-oxazol-3-yl]urea1-(4-(4-amino-7-cyclopropylpyrrolo(2,3-d)pyrimidin-5-yl)-2-fluorophenyl)-3-(5-(1-(trifluoromethyl)cyclopropyl)-1,2-oxazol-3-yl)ureaRefChem:1093845OfirnoflastumHT-61841-(4-(4-amino-7-cyclopropyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-2-fluorophenyl)-3-(5-(1-(trifluoromethyl)cyclopropyl)isoxazol-3-yl)ureaofirnoflast [INN]OFIRNOLAST [USAN]Ofirnoflast (USAN/INN)orb2802265CHEMBL5750400SCHEMBL23966707
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Ofirnoflast
Loading drug network...