IOFLUPANE I 123
methyl (1R,2S,3S,5S)-8-(3-fluoropropyl)-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
Molecular Identity
IOFLUPANE I 123
methyl (1R,2S,3S,5S)-8-(3-fluoropropyl)-3-(4-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
PubChem CID: 3086674
Ioflupane I(123) is an azabicycloalkane that is ecgonine methyl ester in which the N-methyl group is replaced by 3-fluoropropyl and the 3beta-hydroxy group is replaced by 4-(123I)iodophenyl. Used for the imaging of dopamine transporters in the brain of adult patients with potential Parkinsonian Syndromes. It has a role as a radiopharmaceutical and a radioactive imaging agent. It is a methyl ester, an organofluorine compound and an azabicycloalkane. It is functionally related to an ecgonine.
2D Structure
Properties
C18H23FINO2
Molecular Formula
427.30
Molecular Weight
g/mol
427.0769
Exact Mass
Da
4
XLogP
Drug-like (Lipinski: < 5)
29.5
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
4
H-Bond Acceptors
414
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
IOFLUPANE I 123IOFLUPANE I-123ioflupane (123I)123I-IoflupaneDaTSCAN123I-FP-CIT155798-07-5ioflupane I(123)V-09AB03ioflupane ((123)I)V09AB03Ioflupane (123l)Ioflupane, i-123ioflupano (123I)Fp-cit i-123
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to IOFLUPANE I 123
Loading drug network...