Flezurafenib
5-[[(3S)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
Molecular Identity
Flezurafenib
5-[[(3S)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-one
PubChem CID: 162772363
2D Structure
Properties
C26H21FN4O3
Molecular Formula
456.50
Molecular Weight
g/mol
456.1598
Exact Mass
Da
3.6
XLogP
Drug-like (Lipinski: < 5)
89.1
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
6
H-Bond Acceptors
720
Complexity
SMILES
Canonical SMILES
SMILES: C1CC(=O)NC2=NC=CC(=C21)OC3=CC4=C(C=C3)OCC(C4)C5=NC=C(N5)C6=CC=C(C=C6)FIsomeric SMILES
SMILES: C1CC(=O)NC2=NC=CC(=C21)OC3=CC4=C(C=C3)OC[C@@H](C4)C5=NC=C(N5)C6=CC=C(C=C6)FSynonyms(20)
flezurafenib2760321-00-25-[[(3S)-3-[5-(4-fluorophenyl)-1H-imidazol-2-yl]-3,4-dihydro-2H-chromen-6-yl]oxy]-3,4-dihydro-1H-1,8-naphthyridin-2-oneFlezurafenibumflezurafenib [INN]Flezurafenib (USAN/INN)FLEZURAFENIB [USAN]JZP815orb2664284P26TTM6U27CHEMBL6068010SCHEMBL24228888SCHEMBL29516504SCHEMBL30990556GTPL13233
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Flezurafenib
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