Cositecan
(19S)-19-ethyl-19-hydroxy-10-(2-trimethylsilylethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Molecular Identity
Cositecan
(19S)-19-ethyl-19-hydroxy-10-(2-trimethylsilylethyl)-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
PubChem CID: 148202
Cositecan is a pyranoindolizinoquinoline.
2D Structure
Properties
C25H28N2O4Si
Molecular Formula
448.60
Molecular Weight
g/mol
448.1818
Exact Mass
Da
79.7
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
5
H-Bond Acceptors
891
Complexity
SMILES
Canonical SMILES
SMILES: CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)CC[Si](C)(C)C)OIsomeric SMILES
SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C5=CC=CC=C5N=C4C3=C2)CC[Si](C)(C)C)OSynonyms(20)
KarenitecinCositecan203923-89-1BNP1350KarentecinBNP-1350DTXSID9017434024R60NVC41DB 172NSC710270(4S)-4-Ethyl-4-hydroxy-11-(2-(trimethylsilyl)ethyl)-1,12-dihydro-14H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H)-dionecositecanumRefChem:128190DTXCID2096831(19S)-19-ethyl-19-hydroxy-10-(2-(trimethylsilyl)ethyl)-17-oxa-3,13-diazapentacyclo(11.8.0.02,11.0?,?.01?,2?)henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione
Data from PubChem (NCBI)
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Drug Network
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