L-Methylfolate
(2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
Molecular Identity
L-Methylfolate
(2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acid
PubChem CID: 135398561
5-methyltetrahydrofolic acid is a tetrahydrofolic acid that is 5,6,7,8-tetrahydrofolic acid substituted by a methyl group at position 5. It has a role as a human metabolite. It is functionally related to a 5,6,7,8-tetrahydrofolic acid. It is a conjugate acid of a 5-methyltetrahydrofolate(2-).
2D Structure
Properties
C20H25N7O6
Molecular Formula
459.50
Molecular Weight
g/mol
459.1866
Exact Mass
Da
-0.5
XLogP
Drug-like (Lipinski: < 5)
198
TPSA
May have limited oral absorption
7
H-Bond Donors
10
H-Bond Acceptors
865
Complexity
SMILES
Canonical SMILES
SMILES: CN1C(CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)OIsomeric SMILES
SMILES: CN1[C@H](CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)O)C(=O)OSynonyms(20)
Levomefolic acid31690-09-2Levomefolinic acidLMSRL-methylfolateL-5-MTHFNutrifolin8S95DH25XCAcido levomefolico5-methyl-(6s)-tetrahydrofolic acidAcide levomefolique(2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-1,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acidDTXSID00185583(2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioic acidL-methyl folate
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to L-Methylfolate
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