Lut-014
6-methyl-5-N-[3-(7H-purin-6-yl)-2-pyridinyl]-1-N-[3-(trifluoromethoxy)phenyl]isoquinoline-1,5-diamine
Molecular Identity
Lut-014
6-methyl-5-N-[3-(7H-purin-6-yl)-2-pyridinyl]-1-N-[3-(trifluoromethoxy)phenyl]isoquinoline-1,5-diamine
PubChem CID: 138319775
2D Structure
Properties
C27H19F3N8O
Molecular Formula
528.50
Molecular Weight
g/mol
528.1634
Exact Mass
Da
6.2
XLogP
Above Lipinski threshold
114
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
11
H-Bond Acceptors
807
Complexity
SMILES
Canonical SMILES
SMILES: CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC(=CC=C3)OC(F)(F)F)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6Isomeric SMILES
SMILES: CC1=C(C2=C(C=C1)C(=NC=C2)NC3=CC(=CC=C3)OC(F)(F)F)NC4=C(C=CC=N4)C5=C6C(=NC=N5)N=CN6Synonyms(20)
LUT0142274819-46-2LUT-014N5-(3-(7H-Purin-6-yl)pyridin-2-yl)-6-methyl-N1-(3-(trifluoromethoxy)phenyl)isoquinoline-1,5-diamineT4E4I523RYLut 0146-methyl-5-N-[3-(7H-purin-6-yl)pyridin-2-yl]-1-N-[3-(trifluoromethoxy)phenyl]isoquinoline-1,5-diamine6-methyl-5-N-(3-(7H-purin-6-yl)pyridin-2-yl)-1-N-(3-(trifluoromethoxy)phenyl)isoquinoline-1,5-diamineRefChem:201512BRAF Inhibitor LUT014UNII-T4E4I523RYSCHEMBL22356326MFCD32062738AC-35618MS-29779
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Lut-014
Loading drug network...