LY3499446
1-[4-[7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoroquinazolin-4-yl]piperazin-1-yl]prop-2-en-1-one
Molecular Identity
LY3499446
1-[4-[7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoroquinazolin-4-yl]piperazin-1-yl]prop-2-en-1-one
PubChem CID: 146472812
2D Structure
Properties
C22H17ClF2N6OS
Molecular Formula
486.90
Molecular Weight
g/mol
486.0841
Exact Mass
Da
4.4
XLogP
Drug-like (Lipinski: < 5)
116
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
9
H-Bond Acceptors
746
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
LY3499446LY-34994461-(4-(7-(2-Amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoro-quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one2-Propen-1-one, 1-(4-(7-2-amino-7-fluoro-4-benzothiazolyl)-6-chloro-8-fluoro-4-quinazolinyl)-1-piperazinyl)-compound B [WO2022002018A1]compound B (WO2022002018A1)1-[4-[7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoroquinazolin-4-yl]piperazin-1-yl]prop-2-en-1-one1-(4-(7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoroquinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one1-[4-[7-(2-amino-7-fluoro-1,3-benzothiazol-4-yl)-6-chloro-8-fluoro-quinazolin-4-yl]piperazin-1-yl]prop-2-en-1-oneRefChem:154555KRAS G12C Inhibitor LY3499446LY 34994462409131-50-4QZJ1I2EN1VUNII-QZJ1I2EN1V
Data from PubChem (NCBI)
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