Naperiglipron
2-[[4-[6-[(4-cyano-2-fluorophenyl)methoxy]-2-pyridinyl]-2-fluoro-5-methylphenyl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic acid
Molecular Identity
Naperiglipron
2-[[4-[6-[(4-cyano-2-fluorophenyl)methoxy]-2-pyridinyl]-2-fluoro-5-methylphenyl]methyl]-3-[[(2S)-oxetan-2-yl]methyl]benzimidazole-5-carboxylic acid
PubChem CID: 155433819
2D Structure
Properties
C33H26F2N4O4
Molecular Formula
580.60
Molecular Weight
g/mol
580.1922
Exact Mass
Da
5.6
XLogP
Above Lipinski threshold
110
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
9
H-Bond Acceptors
1010
Complexity
SMILES
Canonical SMILES
SMILES: CC1=CC(=C(C=C1C2=NC(=CC=C2)OCC3=C(C=C(C=C3)C#N)F)F)CC4=NC5=C(N4CC6CCO6)C=C(C=C5)C(=O)OIsomeric SMILES
SMILES: CC1=CC(=C(C=C1C2=NC(=CC=C2)OCC3=C(C=C(C=C3)C#N)F)F)CC4=NC5=C(N4C[C@@H]6CCO6)C=C(C=C5)C(=O)OSynonyms(20)
Naperiglipron2572566-11-9Naperiglipron (USAN)LY3549492LY-3549492NAPERIGLIPRON [USAN]naperiglipron [INN]BJN78TT46Sorb3173280CHEMBL5944135SCHEMBL22830391SCHEMBL29562181GTPL14175YQF2518US11655242, Example 2
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Naperiglipron
Loading drug network...