Molecular Identity
Levomepromazine
(2R)-3-(2-methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine
PubChem CID: 72287
Methotrimeprazine is a member of the class of phenothiazines that is 10H-phenothiazine substituted by a (2R)-3-(dimethylamino)-2-methylpropyl group and a methoxy group at positions 10 and 2 respectively. It has a role as an anticoronaviral agent, a non-narcotic analgesic, a phenothiazine antipsychotic drug, a serotonergic antagonist, a dopaminergic antagonist, a cholinergic antagonist and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. It is a tertiary amine and a member of phenothiazines. It derives from a hydride of a 10H-phenothiazine.
2D Structure
Properties
C19H24N2OS
Molecular Formula
328.50
Molecular Weight
g/mol
328.1609
Exact Mass
Da
4.7
XLogP
Drug-like (Lipinski: < 5)
41
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
4
H-Bond Acceptors
378
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
LevomepromazineMETHOTRIMEPRAZINE60-99-1LevopromeNeozineLevomepromazinaNirvanLevomepromazinum2-MethoxytrimeprazineLevopromazineNosinanSK&F 5116RP-7044CL 36467CL 39743
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Levomepromazine
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