Molecular Identity
Levodropropizine
(2S)-3-(4-phenylpiperazin-1-yl)propane-1,2-diol
PubChem CID: 65859
Levodropropizine is a member of the class of N-arylpiperazines that is N-phenylpiperazine in which the amino hydrogen is replaced by a 2,3-dihydroxypropyl group (the S-enantiomer). A peripherally acting antitussive drug that is used as an alternative to opioids. It has a role as an antitussive. It is a secondary alcohol, a N-alkylpiperazine and a N-arylpiperazine.
2D Structure
Properties
C13H20N2O2
Molecular Formula
236.31
Molecular Weight
g/mol
236.1525
Exact Mass
Da
0.6
XLogP
Drug-like (Lipinski: < 5)
46.9
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
4
H-Bond Acceptors
211
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Levodropropizine99291-25-5LevotussDanka(-)-DropropizineLevdropropizine(S)-(-)-DropropizineRapituxLevodropropizinaLevodropropizinumLevoprontL-dropropizineDropropizine, (s)-3O31P6T4G3(-)-(S)-3-(4-Phenyl-1-piperazinyl)-1,2-propanediol
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Levodropropizine
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