Licarbazepine
5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
Molecular Identity
Licarbazepine
5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
PubChem CID: 114709
Licarbazepine is a dibenzoazepine that is 5H-dibenzo[b,f]azepine, reduced across the C-10,11 positions and carrying a carbamoyl substituent at the azepine nitrogen and a hydroxy function at C-10. A voltage-gated sodium channel blocker with anticonvulsant and mood-stabilizing effects, it is related to oxcarbazepine and is an active metabolite of oxcarbazepine. It has a role as an anticonvulsant, a sodium channel blocker and a drug allergen. It is a carboxamide, a dibenzoazepine and a member of ureas. It is functionally related to a carbamazepine.
2D Structure
Properties
C15H14N2O2
Molecular Formula
254.28
Molecular Weight
g/mol
254.1055
Exact Mass
Da
1.4
XLogP
Drug-like (Lipinski: < 5)
66.6
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
2
H-Bond Acceptors
347
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Licarbazepine29331-92-810-HydroxycarbazepinelicarbazepinaXFX1A5KJ3V10,11-Dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide10,11-Dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamideCHEBI:701DTXSID50865484licarbazepinumRefChem:153361DTXCID7081388610,11-MHD10-hydroxy-10,11-dihydro-5H-dibenzo[b,f]azepine-5-carboxamide10,11-Dihydro-10-hydroxycarbamazepine
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Licarbazepine
Loading drug network...