Liothyronine Sodium
sodium (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
Molecular Identity
Liothyronine Sodium
sodium (2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
PubChem CID: 23666110
Liothyronine sodium is the sodium salt of liothyronine. Thought to be more active than levothyroxine and with a rapid (few hours) onset and short duration of action, liothyronine sodium is used in the treatment of hypothyroidism, particularly in cases of hypothyroid coma. It contains a 3,3',5-triiodo-L-thyroninate.
2D Structure
Properties
C15H11I3NNaO4
Molecular Formula
672.95
Molecular Weight
g/mol
672.7720
Exact Mass
Da
95.6
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
5
H-Bond Acceptors
408
Complexity
SMILES
Canonical SMILES
SMILES: C1=CC(=C(C=C1OC2=C(C=C(C=C2I)CC(C(=O)[O-])N)I)I)O.[Na+]Isomeric SMILES
SMILES: C1=CC(=C(C=C1OC2=C(C=C(C=C2I)C[C@@H](C(=O)[O-])N)I)I)O.[Na+]Synonyms(20)
LIOTHYRONINE SODIUM55-06-13,3',5-Triiodo-L-thyronine sodium saltTriostatBasoprocinIbiothyronT3 sodium saltCynomelL-Triiodothyronine sodium saltCytobinLiothyronine sodium salt3,3',5-Triiodo-L-thyronine sodiumLiotrix (t3)Triiodothyronine Sodium Salt3,3',5-Triiodothyronine sodium salt
Data from PubChem (NCBI)
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Trials and conditions connected to Liothyronine Sodium
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