Lisofylline
1-[(5R)-5-hydroxyhexyl]-3,7-dimethylpurine-2,6-dione
Molecular Identity
Lisofylline
1-[(5R)-5-hydroxyhexyl]-3,7-dimethylpurine-2,6-dione
PubChem CID: 501254
(R)-lisofylline is a 1-(5-hydroxyhexyl)-3,7-dimethyl-3,7-dihydro-1H-purine-2,6-dione that has (R)-configuration. A synthetic small molecule which was under development for the treatment of type 1 diabetes mellitus. It has a role as an immunomodulator and an anti-inflammatory agent. It is an enantiomer of a (S)-lisofylline.
2D Structure
Properties
C13H20N4O3
Molecular Formula
280.32
Molecular Weight
g/mol
280.1535
Exact Mass
Da
0.7
XLogP
Drug-like (Lipinski: < 5)
78.7
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
4
H-Bond Acceptors
390
Complexity
SMILES
Canonical SMILES
SMILES: CC(CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C)OIsomeric SMILES
SMILES: C[C@H](CCCCN1C(=O)C2=C(N=CN2C)N(C1=O)C)OSynonyms(20)
(R)-LisofyllineLISOFYLLINE100324-81-0ProTecLisophyllineCT-1501RlisofilinaCT 1501R1-[(5R)-5-hydroxyhexyl]-3,7-dimethylpurine-2,6-dioneLisofylline, (r)-lisofyllinumCT1501R(R)-Lisophylline1-[(R)-5-hydroxyhexyl]theobromineDTXSID7058709
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Lisofylline
Loading drug network...