Molecular Identity
Loperamide hydrochloride
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-N,N-dimethyl-2,2-diphenylbutanamide;hydrochloride
PubChem CID: 71420
Loperamide hydrochloride is a hydrochloride obtained by combining loperamide with one equivalent of hydrochloric acid. Used for treatment of diarrhoea resulting from gastroenteritis or inflammatory bowel disease. It has a role as an anticoronaviral agent, a mu-opioid receptor agonist and an antidiarrhoeal drug. It contains a loperamide(1+).
2D Structure
Properties
C29H34Cl2N2O2
Molecular Formula
513.50
Molecular Weight
g/mol
512.1997
Exact Mass
Da
43.8
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
3
H-Bond Acceptors
623
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Loperamide hydrochloride34552-83-5Loperamide HClImodium A-DArretImodium A-D EZ chewsUp and up anti diarrhealNSC-696356Loperamidi hydrochloridum77TI35393CR 18,5534-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidine butyramide HClCHEBI:65334-(4-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenylpiperidine-1-butyramide monohydrochloride4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-alpha,alpha-diphenyl-1-piperidinebutyramide monohydrochloride
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Loperamide hydrochloride
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