Lornoxicam
6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide
Molecular Identity
Lornoxicam
6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-pyridin-2-ylthieno[2,3-e]thiazine-3-carboxamide
PubChem CID: 54690031
Lornoxicam is a thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic and an antipyretic. It is a member of pyridines, a monocarboxylic acid amide, an organochlorine compound, a thienothiazine and a heteroaryl hydroxy compound.
2D Structure
Properties
C13H10ClN3O4S2
Molecular Formula
371.80
Molecular Weight
g/mol
370.9801
Exact Mass
Da
2.1
XLogP
Drug-like (Lipinski: < 5)
136
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
7
H-Bond Acceptors
634
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Lornoxicam70374-39-9ChlortenoxicamXefocamXefoLorcamLornoxicamumRo 13-9297CCRIS 8589NSC-759620Ro-13-9297ER09126G7ARo-1392972H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXAMIDE, 6-CHLORO-4-HYDROXY-2-METHYL-N-2-PYRIDINYL-, 1,1-DIOXIDECHEBI:31783
Data from PubChem (NCBI)
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