Mak-683
N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methyl-3-pyridinyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
Molecular Identity
Mak-683
N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methyl-3-pyridinyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
PubChem CID: 121412508
2D Structure
Properties
C20H17FN6O
Molecular Formula
376.40
Molecular Weight
g/mol
376.1448
Exact Mass
Da
3.4
XLogP
Drug-like (Lipinski: < 5)
77.2
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
7
H-Bond Acceptors
541
Complexity
SMILES
Canonical SMILES
SMILES: CC1=C(C=CC=N1)C2=CN=C(N3C2=NN=C3)NCC4=C(C=CC5=C4CCO5)FIsomeric SMILES
SMILES: CC1=C(C=CC=N1)C2=CN=C(N3C2=NN=C3)NCC4=C(C=CC5=C4CCO5)FSynonyms(20)
MAK683EED inhibitor-1MAK-683N-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl]-8-(2-methylpyridin-3-yl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amineexample 2 [WO2016103155A1]1,2,4-Triazolo(4,3-C)pyrimidin-5-amine, N-((5-fluoro-2,3-dihydro-4-benzofuranyl)methyl)-8-(2-methyl-3-pyridinyl)-N-((5-Fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl)-8-(2-methylpyridin-3-yl)(1,2,4)triazolo(4,3-C)pyrimidin-5-amineexample 2 (WO2016103155A1)N-((5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methyl)-8-(2-methylpyridin-3-yl)-(1,2,4)triazolo(4,3-c)pyrimidin-5-amineRefChem:155328EED Inhibitor MAK683EED PPI Inhibitor MAK683Ectodermal Embryonic Development Inhibitor MAK683EED Protein-protein Interaction Inhibitor MAK6831951408-58-4
Data from PubChem (NCBI)
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