MK-8189
2-methyl-6-[[(1S,2S)-2-(5-methyl-2-pyridinyl)cyclopropyl]methoxy]-N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]pyrimidin-4-amine
Molecular Identity
MK-8189
2-methyl-6-[[(1S,2S)-2-(5-methyl-2-pyridinyl)cyclopropyl]methoxy]-N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]pyrimidin-4-amine
PubChem CID: 71271414
2D Structure
Properties
C19H22N6OS
Molecular Formula
382.50
Molecular Weight
g/mol
382.1576
Exact Mass
Da
3.1
XLogP
Drug-like (Lipinski: < 5)
114
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
8
H-Bond Acceptors
485
Complexity
SMILES
Canonical SMILES
SMILES: CC1=CN=C(C=C1)C2CC2COC3=NC(=NC(=C3)NCC4=NN=C(S4)C)CIsomeric SMILES
SMILES: CC1=CN=C(C=C1)[C@H]2C[C@@H]2COC3=NC(=NC(=C3)NCC4=NN=C(S4)C)CSynonyms(20)
MK-81891424371-93-6MK81897M430JI73B2-Methyl-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}-N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]pyrimidin-4-amine2-methyl-6-[[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy]-N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]pyrimidin-4-amine2-methyl-6-(((1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)-N-((5-methyl-1,3,4-thiadiazol-2-yl)methyl)pyrimidin-4-amineRefChem:9259702-methyl-6-((2-(5-methylpyridin-2-yl)cyclopropyl)methoxy)-N-((5-methyl-1,3,4-thiadiazol-2-yl)methyl)pyrimidin-4-amine2-METHYL-N-((5-METHYL-1,3,4-THIADIAZOL-2-YL)METHYL)-6-(((1S,2S)-2-(5-METHYLPYRIDIN-2-YL)CYCLOPROPYL)METHOXY)PYRIMIDIN-4-AMINEelpipodectelpipodect [INN]2-methyl-N-[(5-methyl-1,3,4-thiadiazol-2-yl)methyl]-6-{[(1S,2S)-2-(5-methylpyridin-2-yl)cyclopropyl]methoxy}pyrimidin-4-amineorb1744148CHEMBL5314924
Data from PubChem (NCBI)
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