Molecular Identity
Pergolide Mesylate
(6aR,9R,10aR)-9-(methylsulfanylmethyl)-7-propyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline;methanesulfonic acid
PubChem CID: 47812
Pergolide mesylate is a methanesulfonate salt obtained from pergolide by mixing eqimolar amount of pergolide and methanesulfonic acid. A dopamine D2 receptor agonist which also has D1 and D2 agonist properties, it is used in the management of Parkinson's disease, although it was withdrawn from the U.S. and Canadian markets in 2007 due to an increased risk of cardiac valve dysfunction. It has a role as a geroprotector, an antiparkinson drug and a dopamine agonist. It contains a pergolide(1+).
2D Structure
Properties
C20H30N2O3S2
Molecular Formula
410.60
Molecular Weight
g/mol
410.1698
Exact Mass
Da
107
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
5
H-Bond Acceptors
480
Complexity
SMILES
Canonical SMILES
SMILES: CCCN1CC(CC2C1CC3=CNC4=CC=CC2=C34)CSC.CS(=O)(=O)OIsomeric SMILES
SMILES: CCCN1C[C@@H](C[C@H]2[C@H]1CC3=CNC4=CC=CC2=C34)CSC.CS(=O)(=O)OSynonyms(20)
PERGOLIDE MESYLATE66104-23-2Pergolide MethanesulfonatePergolide mesilateDTXSID6040583LY127809NSC-319773NSC-758442LY 127809LY-12780955B9HQY616CHEBI:8021DTXCID40205838beta-((Methylthio)methyl)-6-propylergoline monomethanesulfonateNSC319773
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Pergolide Mesylate
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