Molecular Identity
meclofenamic acid
2-(2,6-dichloro-3-methylanilino)benzoic acid
PubChem CID: 4037
Meclofenamic acid is an aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,6-dichloro-3-methylphenyl group. A non-steroidal anti-inflammatory drug, it is used as the sodium salt for the treatment of dysmenorrhoea (painful periods), osteoarthritis and rheumatoid arthritis. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, an antipyretic, an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor, an antineoplastic agent, an anticonvulsant, an antirheumatic drug and an EC 1.13.11.34 (arachidonate 5-lipoxygenase) inhibitor. It is an aminobenzoic acid, an organochlorine compound and a secondary amino compound. It is a conjugate acid of a meclofenamic acid(1-).
2D Structure
Properties
C14H11Cl2NO2
Molecular Formula
296.10
Molecular Weight
g/mol
295.0167
Exact Mass
Da
5.2
XLogP
Above Lipinski threshold
49.3
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
3
H-Bond Acceptors
327
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
meclofenamic acidmeclofenamate644-62-2Arquel2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acidAcido meclofenamicoAcide meclofenamiqueINF 4668Acidum meclofenamicumN-(2,6-Dichloro-m-tolyl)anthranilic acidCI-583INF-4668MeclomenN-(3-Methyl-2,6-dichlorophenyl)anthranilic acid2-((2,6-Dichloro-3-methylphenyl)amino)benzoic acid
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to meclofenamic acid
Loading drug network...