Molecular Identity
Thioridazine
10-[2-(1-methylpiperidin-2-yl)ethyl]-2-methylsulfanylphenothiazine
PubChem CID: 5452
Thioridazine is a phenothiazine derivative having a methylsulfanyl subsitituent at the 2-position and a (1-methylpiperidin-2-yl)ethyl] group at the N-10 position. It has a role as an alpha-adrenergic antagonist, a H1-receptor antagonist, a serotonergic antagonist, a dopaminergic antagonist, a first generation antipsychotic, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor and an EC 1.8.1.12 (trypanothione-disulfide reductase) inhibitor. It is a member of piperidines and a member of phenothiazines. It contains a methylsulfanyl group.
2D Structure
Properties
C21H26N2S2
Molecular Formula
370.60
Molecular Weight
g/mol
370.1537
Exact Mass
Da
5.9
XLogP
Above Lipinski threshold
57.1
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
4
H-Bond Acceptors
432
Complexity
SMILES
Canonical SMILES
SMILES: CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SCIsomeric SMILES
SMILES: CN1CCCCC1CCN2C3=CC=CC=C3SC4=C2C=C(C=C4)SCSynonyms(20)
thioridazine50-52-2MellarilThioridazinMelleretteSonapaxMallorylMelerilMellerilMellaril-SMallorolMelleretsdl-ThioridazineMellerettenTioridazina
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Thioridazine
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