Molecular Identity
Midodrine Hydrochloride
2-amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide;hydrochloride
PubChem CID: 18340
Midodrine hydrochloride is a hydrochloride resulting from the combination of equimolar amounts of midodrine and hydrogen chloride. Midodrine is a direct-acting sympathomimetic with selective alpha-adrenergic agonist activity. The hydrochloride salt is used as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine. It has a role as a sympathomimetic agent, an alpha-adrenergic agonist and a vasoconstrictor agent. It contains a midodrine(1+).
2D Structure
Properties
C12H19ClN2O4
Molecular Formula
290.74
Molecular Weight
g/mol
290.1033
Exact Mass
Da
93.8
TPSA
Good oral absorption (< 140 A²)
4
H-Bond Donors
5
H-Bond Acceptors
262
Complexity
SMILES
Canonical SMILES
SMILES: COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.ClIsomeric SMILES
SMILES: COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.ClSynonyms(20)
MIDODRINE HYDROCHLORIDE43218-56-0Midodrine HCLPro-AmatineProAmatineHipertanAmatineOrvatenGutronMidamineSt. Peter 224(+-)-Midodrine hydrochlorideMetligineMidodrine MonohydrochlorideA-4020 Linz
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Midodrine Hydrochloride
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