Meloxicam
4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxamide
Molecular Identity
Meloxicam
4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1lambda6,2-benzothiazine-3-carboxamide
PubChem CID: 54677470
Meloxicam is a benzothiazine that is piroxicam in which the pyridin-2-yl group is replaced by a 5-methyl-1,3-thiazol-2-yl group. A non-steroidal anti-inflammatory drug and selective inhibitor of COX-2, it is used particularly for the management of rheumatoid arthritis. It has a role as a non-steroidal anti-inflammatory drug, an analgesic, an antirheumatic drug and a cyclooxygenase 2 inhibitor. It is a monocarboxylic acid amide, a member of 1,3-thiazoles and a benzothiazine.
2D Structure
Properties
C14H13N3O4S2
Molecular Formula
351.40
Molecular Weight
g/mol
351.0347
Exact Mass
Da
3
XLogP
Drug-like (Lipinski: < 5)
136
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
7
H-Bond Acceptors
628
Complexity
SMILES
Canonical SMILES
SMILES: CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)OIsomeric SMILES
SMILES: CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)OSynonyms(20)
meloxicam71125-38-7MobicMetacamMobicoxMovalisMovatecMobecCoxicamMeloxivetMelfaxUH-AC 62XXMeloxicamumMeloxidolorMeloxoral
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Meloxicam
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