LXH254
N-[3-[2-(2-hydroxyethoxy)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
Molecular Identity
LXH254
N-[3-[2-(2-hydroxyethoxy)-6-morpholin-4-yl-4-pyridinyl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamide
PubChem CID: 90456533
2D Structure
Properties
C25H25F3N4O4
Molecular Formula
502.50
Molecular Weight
g/mol
502.1828
Exact Mass
Da
3.2
XLogP
Drug-like (Lipinski: < 5)
96.8
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
10
H-Bond Acceptors
709
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
LXH2541800398-38-2NaporafenibLXH-254Pan-raf inhibitor LXH25415JL80DG6HERAS-254LXH 254N-[3-[2-(2-hydroxyethoxy)-6-morpholin-4-ylpyridin-4-yl]-4-methylphenyl]-2-(trifluoromethyl)pyridine-4-carboxamideN-(3-(2-(2-hydroxyethoxy)-6-morpholin-4-ylpyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)pyridine-4-carboxamideRefChem:164782pan-RAF Kinase Inhibitor LXH254Raf Family Kinase Inhibitor LXH254N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamideLXH254 free base
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to LXH254
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