Molecular Identity
nicotinamide
pyridine-3-carboxamide
PubChem CID: 936
Nicotinamide is a pyridinecarboxamide that is pyridine in which the hydrogen at position 3 is replaced by a carboxamide group. It has a role as a geroprotector, an antioxidant, a cofactor, a metabolite, an EC 3.5.1.98 (histone deacetylase) inhibitor, an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor, a neuroprotective agent, an anti-inflammatory agent, a Sir2 inhibitor, a mouse metabolite, a Saccharomyces cerevisiae metabolite, an Escherichia coli metabolite and a human urinary metabolite. It is a vitamin B3, a pyridinecarboxamide and a pyridine alkaloid. It is functionally related to a nicotinic acid.
2D Structure
Properties
C6H6N2O
Molecular Formula
122.12
Molecular Weight
g/mol
122.0480
Exact Mass
Da
-0.4
XLogP
Drug-like (Lipinski: < 5)
56
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
2
H-Bond Acceptors
114
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
nicotinamideniacinamide98-92-03-Pyridinecarboxamidepyridine-3-carboxamideNicotinic acid amideAminicotinAmixicotynBenicotDipegylPapulexPelonin amideNicotilamideEndobionHansamid
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to nicotinamide
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