Molecular Identity
norfloxacin
1-ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
PubChem CID: 4539
Norfloxacin is a quinolinemonocarboxylic acid with broad-spectrum antibacterial activity against most gram-negative and gram-positive bacteria. Norfloxacin is bactericidal and its mode of action depends on blocking of bacterial DNA replication by binding itself to an enzyme called DNA gyrase. It has a role as a xenobiotic, an antibacterial drug, a DNA synthesis inhibitor and an environmental contaminant. It is a quinolone, a quinolinemonocarboxylic acid, a N-arylpiperazine, a quinolone antibiotic and a fluoroquinolone antibiotic.
2D Structure
Properties
C16H18FN3O3
Molecular Formula
319.33
Molecular Weight
g/mol
319.1332
Exact Mass
Da
-1
XLogP
Drug-like (Lipinski: < 5)
72.9
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
7
H-Bond Acceptors
519
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
norfloxacin70458-96-7NoroxinNorfloxacineChibroxinBaccidalSebercimNorfloxacinoMK-366NorfloxacinumFulgram1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acidAM-715NFLX1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to norfloxacin
Loading drug network...