Oprozomib
N-[(2S)-3-methoxy-1-[[(2S)-3-methoxy-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
Molecular Identity
Oprozomib
N-[(2S)-3-methoxy-1-[[(2S)-3-methoxy-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamide
PubChem CID: 25067547
2D Structure
Properties
C25H32N4O7S
Molecular Formula
532.60
Molecular Weight
g/mol
532.1992
Exact Mass
Da
1.1
XLogP
Drug-like (Lipinski: < 5)
176
TPSA
May have limited oral absorption
3
H-Bond Donors
9
H-Bond Acceptors
825
Complexity
SMILES
Canonical SMILES
SMILES: CC1=NC=C(S1)C(=O)NC(COC)C(=O)NC(COC)C(=O)NC(CC2=CC=CC=C2)C(=O)C3(CO3)CIsomeric SMILES
SMILES: CC1=NC=C(S1)C(=O)N[C@@H](COC)C(=O)N[C@@H](COC)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)[C@]3(CO3)CSynonyms(20)
Oprozomib935888-69-0ONX-0912PR-047ONX 0912MZ37792Y8JN-[(2S)-3-methoxy-1-[[(2S)-3-methoxy-1-[[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]-2-methyl-1,3-thiazole-5-carboxamideDTXSID201025950(2S)-3-methoxy-2-[(2S)-3-methoxy-2-[(2-methyl-1,3-thiazol-5-yl)formamido]propanamido]-N-[(2S)-1-[(2R)-2-methyloxiran-2-yl]-1-oxo-3-phenylpropan-2-yl]propanamideoprozomibum(2S)-3-methoxy-2-((2S)-3-methoxy-2-((2-methyl-1,3-thiazol-5-yl)formamido)propanamido)-N-((2S)-1-((2R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)propanamideN-((2S)-3-methoxy-1-(((2S)-3-methoxy-1-(((2S)-1-((2R)-2-methyloxiran-2-yl)-1-oxo-3-phenylpropan-2-yl)amino)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)-2-methyl-1,3-thiazole-5-carboxamideRefChem:928244Proteasome Inhibitor ONX 0912DTXCID801510202
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Oprozomib
Loading drug network...