Molecular Identity
Orphenadrine
N,N-dimethyl-2-[(2-methylphenyl)-phenylmethoxy]ethanamine
PubChem CID: 4601
Orphenadrine is a tertiary amino compound which is the phenyl-o-tolylmethyl ether of 2-(dimethylamino)ethanol. It has a role as a H1-receptor antagonist, an antiparkinson drug, a muscarinic antagonist, a parasympatholytic, a muscle relaxant, a NMDA receptor antagonist and an antidyskinesia agent. It is an ether and a tertiary amino compound.
2D Structure
Properties
C18H23NO
Molecular Formula
269.40
Molecular Weight
g/mol
269.1780
Exact Mass
Da
3.8
XLogP
Drug-like (Lipinski: < 5)
12.5
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
2
H-Bond Acceptors
260
Complexity
SMILES
Canonical SMILES
SMILES: CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)CIsomeric SMILES
SMILES: CC1=CC=CC=C1C(C2=CC=CC=C2)OCCN(C)CSynonyms(20)
orphenadrineOrphenadrin83-98-7Orphenadineo-MethyldiphenhydramineOrphenedrineBrocadisipalOrfenadrina2-MethyldiphenhydramineMefenamineOrphenadrinumo-Monomethyldiphenhydramine2-(Phenyl-o-tolylmethoxy)ethyldimethylamineMephenamineN,N-dimethyl-2-(phenyl(o-tolyl)methoxy)ethanamine
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Orphenadrine
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