Paltimatrectinib
5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-3-[4-(trifluoromethyl)pyrazol-1-yl]pyrazolo[1,5-a]pyrimidine
Molecular Identity
Paltimatrectinib
5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-3-[4-(trifluoromethyl)pyrazol-1-yl]pyrazolo[1,5-a]pyrimidine
PubChem CID: 155753054
2D Structure
Properties
C20H15F5N6
Molecular Formula
434.40
Molecular Weight
g/mol
434.1278
Exact Mass
Da
3.9
XLogP
Drug-like (Lipinski: < 5)
51.3
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
9
H-Bond Acceptors
638
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Paltimatrectinib2353522-15-1Paltimatrectinib [INN]SP4MKH8Y5J5-[(2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl]-3-[4-(trifluoromethyl)pyrazol-1-yl]pyrazolo[1,5-a]pyrimidine(R)-5-(2-(2,5-Difluorophenyl) pyrrolidin-1-yl)-3-(4-(trifluoromethyl)-1H-pyrazol-1-yl)pyrazolo(1,5-a) pyrimidineexample I-147 [US20210094956A1]Pyrazolo(1,5-a)pyrimidine, 5-((2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl)-3-(4-(trifluoromethyl)-1H-pyrazol-1-yl)-Pyrazolo[1,5-a]pyrimidine, 5-[(2R)-2-(2,5-difluorophenyl)-1-pyrrolidinyl]-3-[4-(trifluoromethyl)-1H-pyrazol-1-yl]-example I-147 (US20210094956A1)5-((2R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)-3-(4-(trifluoromethyl)pyrazol-1-yl)pyrazolo(1,5-a)pyrimidineRefChem:169775PBI-200UNII-SP4MKH8Y5JPPI-5278
Data from PubChem (NCBI)
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