Penciclovir
2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1H-purin-6-one
Molecular Identity
Penciclovir
2-amino-9-[4-hydroxy-3-(hydroxymethyl)butyl]-1H-purin-6-one
PubChem CID: 135398748
Penciclovir is a member of the class of 2-aminopurines that is guanine in which the hydrogen at position 9 is substituted by a 4-hydroxy-3-(hydroxymethyl)but-1-yl group. An antiviral drug, it is administered topically for treatment of herpes labialis. A prodrug, famciclovir, is used for oral administration. It has a role as an antiviral drug. It is a member of 2-aminopurines and a member of propane-1,3-diols. It is functionally related to a guanine.
2D Structure
Properties
C10H15N5O3
Molecular Formula
253.26
Molecular Weight
g/mol
253.1175
Exact Mass
Da
-1.9
XLogP
Drug-like (Lipinski: < 5)
126
TPSA
Good oral absorption (< 140 A²)
4
H-Bond Donors
5
H-Bond Acceptors
344
Complexity
SMILES
Canonical SMILES
SMILES: C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)NIsomeric SMILES
SMILES: C1=NC2=C(N1CCC(CO)CO)N=C(NC2=O)NSynonyms(20)
penciclovir39809-25-1DenavirBRL-39123PenciclovirumVectavirBRL 391232-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one9-(4-Hydroxy-3-(hydroxymethyl)butyl)guanineCCRIS 9213DTXSID90464919-(4-HYDROXY-3-(HYDROXYMETHYL)BUT-1-YL)GUANINE359HUE8FJC9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanineNSC-759624
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Penciclovir
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