eribaxaban
(2R,4R)-1-N-(4-chlorophenyl)-2-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-4-methoxypyrrolidine-1,2-dicarboxamide
Molecular Identity
eribaxaban
(2R,4R)-1-N-(4-chlorophenyl)-2-N-[2-fluoro-4-(2-oxo-1-pyridinyl)phenyl]-4-methoxypyrrolidine-1,2-dicarboxamide
PubChem CID: 11634458
Eribaxaban is a member of the class of pyrrolidines that is (2R,4R)-N1-(p-chlorophenyl)-4-methoxypyrrolidine-1,2-dicarboxamide in which the nitrogen of the 2-carbamoyl group has been substituted by a 2-fluoro-4-(2-oxopyridin-1(2H)-yl)phenyl group. It is a synthetic organic anticoagulant compound that targets activated factor Xa in the coagulation cascade. It has a role as an anticoagulant, a serine protease inhibitor and an EC 3.4.21.6 (coagulation factor Xa) inhibitor. It is a secondary carboxamide, a pyridone, a member of pyrrolidines, a member of ureas, a member of monochlorobenzenes and a member of monofluorobenzenes.
2D Structure
Properties
C24H22ClFN4O4
Molecular Formula
484.90
Molecular Weight
g/mol
484.1314
Exact Mass
Da
2.9
XLogP
Drug-like (Lipinski: < 5)
91
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
5
H-Bond Acceptors
832
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
eribaxabanEribaxaban (USAN)Eribaxaban [USAN]eribaxabanumEribaxaban [USAN:INN]UNII-5FCH6YDY7Z5FCH6YDY7ZPD 348292PD 348,292PD-348292ERIBAXABAN [INN]PD-348ERIBAXABAN [WHO-DD]CHEBI:140420DTXSID60201915
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to eribaxaban
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