PF-06821497
5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1-one
Molecular Identity
PF-06821497
5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1-one
PubChem CID: 118572065
2D Structure
Properties
C22H24Cl2N2O5
Molecular Formula
467.30
Molecular Weight
g/mol
466.1062
Exact Mass
Da
2.1
XLogP
Drug-like (Lipinski: < 5)
77.1
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
5
H-Bond Acceptors
797
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
PF-068214971844849-10-0MevrometostatS4L4MM20B6PF068214971(2H)-Isoquinolinone, 5,8-dichloro-2-((1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl)-3,4-dihydro-7-((R)-methoxy-3-oxetanylmethyl)-1(2H)-Isoquinolinone, 5,8-dichloro-2-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-3,4-dihydro-7-[(R)-methoxy-3-oxetanylmethyl]-5,8-dichloro-2-((4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl)-7-((R)-methoxy(oxetan-3-yl)methyl)-3,4-dihydroisoquinolin-1-one5,8-dichloro-2-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-7-[(R)-methoxy(oxetan-3-yl)methyl]-3,4-dihydroisoquinolin-1-onePF 06821497RefChem:172264EZH2 Inhibitor PF-068214975,8-dichloro-7-((R)-methoxy(oxetan-3-yl)methyl)-2-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1,2,3,4-tetrahydroisoquinolin-1-oneUNII-S4L4MM20B6CHEMBL4080228
Data from PubChem (NCBI)
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