PF-06873600
6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one
Molecular Identity
PF-06873600
6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrido[2,3-d]pyrimidin-7-one
PubChem CID: 134247638
2D Structure
Properties
C20H27F2N5O4S
Molecular Formula
471.50
Molecular Weight
g/mol
471.1752
Exact Mass
Da
1.4
XLogP
Drug-like (Lipinski: < 5)
124
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
10
H-Bond Acceptors
859
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
PF-06873600EbvaciclibEbvaciclib [USAN]3B512HJD65EBVACICLIB [INN]6-(difluoromethyl)-8-[(1R,2R)-2-hydroxy-2-methylcyclopentyl]-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrido[2,3-d]pyrimidin-7-oneUNII-3B512HJD65PF06873600Ebvaciclib (USAN)PYRIDO(2,3-D)PYRIMIDIN-7(8H)-ONE, 6-(DIFLUOROMETHYL)-8-((1R,2R)-2-HYDROXY-2-METHYLCYCLOPENTYL)-2-((1-(METHYLSULFONYL)-4-PIPERIDINYL)AMINO)-6-(difluoromethyl)-8-((1R,2R)-2-hydroxy-2-methylcyclopentyl)-2-((1-methylsulfonylpiperidin-4-yl)amino)pyrido(2,3-d)pyrimidin-7-oneRefChem:136191CDK Inhibitor PF-06873600PF 068736006-(DIFLUOROMETHYL)-8-((1R,2R)-2-HYDROXY-2-METHYLCYCLOPENTYL)-2-((1-(METHYLSULFONYL)PIPERIDIN-4-YL) AMINO)PYRIDO(2,3-D)PYRIMIDIN-7(8H)-ONE
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to PF-06873600
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