Pf-07258669
(2R)-2-(5-fluoro-2-methoxy-4-pyridinyl)-1-[(2S)-7-methyl-6-pyrimidin-2-ylspiro[3,4-dihydro-1H-1,8-naphthyridine-2,3'-pyrrolidine]-1'-yl]propan-1-one
Molecular Identity
Pf-07258669
(2R)-2-(5-fluoro-2-methoxy-4-pyridinyl)-1-[(2S)-7-methyl-6-pyrimidin-2-ylspiro[3,4-dihydro-1H-1,8-naphthyridine-2,3'-pyrrolidine]-1'-yl]propan-1-one
PubChem CID: 164889476
2D Structure
Properties
C25H27FN6O2
Molecular Formula
462.50
Molecular Weight
g/mol
462.2180
Exact Mass
Da
2.9
XLogP
Drug-like (Lipinski: < 5)
93.1
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
8
H-Bond Acceptors
724
Complexity
SMILES
Canonical SMILES
SMILES: CC1=C(C=C2CCC3(CCN(C3)C(=O)C(C)C4=CC(=NC=C4F)OC)NC2=N1)C5=NC=CC=N5Isomeric SMILES
SMILES: CC1=C(C=C2CC[C@@]3(CCN(C3)C(=O)[C@H](C)C4=CC(=NC=C4F)OC)NC2=N1)C5=NC=CC=N5Synonyms(20)
PF-07258669(2R)-2-(5-fluoro-2-methoxypyridin-4-yl)-1-[(2S)-7-methyl-6-(pyrimidin-2-yl)-3,4-dihydro-1H-spiro[1,8-naphthyridine-2,3'-pyrrolidin]-1'-yl]propan-1-one(2R)-2-(5-FLUORO-2-METHOXYPYRIDIN-4-YL)-1-((2S)-7-METHYL-6-(PYRIMIDIN-2-YL)-3,4-DIHYDRO-1H-SPIRO(1,8-NAPHTHYRIDINE-2,3'-PYRROLIDIN)-1'-YL)PROPAN-1-ONERefChem:1722702755890-53-8CHEMBL5183637(2R)-2-(5-Fluoro-2-methoxypyridin-4-yl)-1-[(2S)-7-methyl-6-pyrimidin-2-ylspiro[3,4-dihydro-1H-1,8-naphthyridine-2,3'-pyrrolidine]-1'-yl]propan-1-oneorb1739954SCHEMBL24853368SCHEMBL30318564GTPL12158GLXC-27032EX-A6871BDBM50598696MFCD34789488
Data from PubChem (NCBI)
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