Tinlorafenib
N-[2-chloro-3-[(3,5-dimethyl-4-oxoquinazolin-6-yl)amino]-4-fluorophenyl]-3-fluoropropane-1-sulfonamide
Molecular Identity
Tinlorafenib
N-[2-chloro-3-[(3,5-dimethyl-4-oxoquinazolin-6-yl)amino]-4-fluorophenyl]-3-fluoropropane-1-sulfonamide
PubChem CID: 155434855
2D Structure
Properties
C19H19ClF2N4O3S
Molecular Formula
456.90
Molecular Weight
g/mol
456.0834
Exact Mass
Da
3.2
XLogP
Drug-like (Lipinski: < 5)
99.3
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
8
H-Bond Acceptors
751
Complexity
SMILES
Canonical SMILES
SMILES: CC1=C(C=CC2=C1C(=O)N(C=N2)C)NC3=C(C=CC(=C3Cl)NS(=O)(=O)CCCF)FIsomeric SMILES
SMILES: CC1=C(C=CC2=C1C(=O)N(C=N2)C)NC3=C(C=CC(=C3Cl)NS(=O)(=O)CCCF)FSynonyms(20)
Tinlorafenib2573781-75-4ARRY-461Tinlorafenib [USAN]JNJ5N2RH5WPF-07284890AR00504461ARRY461N-(2-chloro-3-((3,5-dimethyl-4-oxo-3,4-dihydroquinazolin-6-yl)amino)-4-fluorophenyl)-3-fluoropropane-1-sulfonamide1-Propanesulfonamide, N-(2-chloro-3-((3,4-dihydro-3,5-dimethyl-4-oxo-6-quinazolinyl)amino)-4-fluorophenyl)-3-fluoro-Tinlorafenib (USAN)PF07284890RefChem:190069ARRY 461BRAF Inhibitor PF-07284890
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Tinlorafenib
Loading drug network...