MEK-IN-6
8-(2-fluoro-4-methylsulfanylanilino)-2-(2-hydroxyethoxy)-7-methyl-3,4-dihydro-2,7-naphthyridine-1,6-dione
Molecular Identity
MEK-IN-6
8-(2-fluoro-4-methylsulfanylanilino)-2-(2-hydroxyethoxy)-7-methyl-3,4-dihydro-2,7-naphthyridine-1,6-dione
PubChem CID: 165386441
2D Structure
Properties
C18H20FN3O4S
Molecular Formula
393.40
Molecular Weight
g/mol
393.1159
Exact Mass
Da
1.4
XLogP
Drug-like (Lipinski: < 5)
107
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
7
H-Bond Acceptors
669
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
MEK-IN-62845151-86-0HY-153445polfurmetinibPolfermetinibpolfurmetinib [INN]Polfurmetinib (USAN)GST8GSH94BPOLFERMETINIB [USAN]ARRY-134orb1944374SCHEMBL24685478SCHEMBL29908281GTPL14063Example 69 [WO2022208391A1]
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to MEK-IN-6
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