Paromomycin Sulfate
(2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-diamino-2-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol;sulfuric acid
Molecular Identity
Paromomycin Sulfate
(2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(2R,3S,4R,5S)-5-[(1R,2R,3S,5R,6S)-3,5-diamino-2-[(2S,3R,4R,5S,6R)-3-amino-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6-hydroxycyclohexyl]oxy-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxyoxane-3,4-diol;sulfuric acid
PubChem CID: 441375
Paromomycin sulfate is an aminoglycoside sulfate salt resulting from the treatment of paromomycin with sulfuric acid. A broad-spectrum antibiotic, it is used for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. It has a role as an antiparasitic agent, an anthelminthic drug, an antiprotozoal drug and an antibacterial drug. It is functionally related to a paromomycin.
2D Structure
Properties
C23H47N5O18S
Molecular Formula
713.70
Molecular Weight
g/mol
713.2637
Exact Mass
Da
430
TPSA
May have limited oral absorption
15
H-Bond Donors
23
H-Bond Acceptors
952
Complexity
SMILES
Canonical SMILES
SMILES: C1C(C(C(C(C1N)OC2C(C(C(C(O2)CO)O)O)N)OC3C(C(C(O3)CO)OC4C(C(C(C(O4)CN)O)O)N)O)O)N.OS(=O)(=O)OIsomeric SMILES
SMILES: C1[C@H]([C@@H]([C@H]([C@@H]([C@H]1N)O[C@@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)N)O[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O[C@@H]4[C@@H]([C@H]([C@@H]([C@@H](O4)CN)O)O)N)O)O)N.OS(=O)(=O)OSynonyms(20)
Paromomycin sulfate1263-89-4GabbromicinaGabbroralHumagelAminosidin sulfateAminosidine sulfateAminosidine sulphateFarminosidinAminoxidinFarmiglucinSinosidPargonylHumycin sulfateParomomycin sulphate
Data from PubChem (NCBI)
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Trials and conditions connected to Paromomycin Sulfate
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