PLX8394
(3R)-N-[3-[5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
Molecular Identity
PLX8394
(3R)-N-[3-[5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl]-2,4-difluorophenyl]-3-fluoropyrrolidine-1-sulfonamide
PubChem CID: 90116675
2D Structure
Properties
C25H21F3N6O3S
Molecular Formula
542.50
Molecular Weight
g/mol
542.1348
Exact Mass
Da
2.8
XLogP
Drug-like (Lipinski: < 5)
129
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
11
H-Bond Acceptors
976
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
PLX83941393466-87-9PlixorafenibPLX-8394FORE8394FORE-8394PLX 8394J2L7Z273SG(R)-N-(3-(5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamide1-Pyrrolidinesulfonamide, N-(3-((5-(2-cyclopropyl-5-pyrimidinyl)-1H-pyrrolo(2,3-b)pyridin-3-yl)carbonyl)-2,4-difluorophenyl)-3-fluoro-, (3R)-(R)-N-(3-(5-(2-cyclopropylpyrimidin-5-yl)-1H-pyrrolo(2,3-b)pyridine-3-carbonyl)-2,4-difluorophenyl)-3-fluoropyrrolidine-1-sulfonamideRefChem:174942BRAF Inhibitor PLX8394BRAF Inhibitor FORE8394FORE 8394
Data from PubChem (NCBI)
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