Molecular Identity
Droxicam
5-methyl-6,6-dioxo-3-pyridin-2-yl-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4-dione
PubChem CID: 65679
Droxicam is an organic heterotricyclic compound that is 2H,5H-[1,3]oxazino[5,6-c][1,2]benzothiazine-2,4(3H)-dione 6,6-dioxide substituted at positions 3 and 5 by pyridin-2-yl and methyl groups respectively. A prodrug of piroxicam, it is used for the relief of pain and inflammation in musculoskeletal disorders such as rheumatoid arthritis and osteoarthritis. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, a prodrug, a platelet aggregation inhibitor, a cyclooxygenase 1 inhibitor and a hepatotoxic agent. It is a member of pyridines and an organic heterotricyclic compound. It is functionally related to a piroxicam.
2D Structure
Properties
C16H11N3O5S
Molecular Formula
357.30
Molecular Weight
g/mol
357.0419
Exact Mass
Da
1.2
XLogP
Drug-like (Lipinski: < 5)
105
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
7
H-Bond Acceptors
741
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Droxicam90101-16-9DroxicamumF24ADO1E2DDTXSID70238035CHEBI:76133RefChem:1358475-methyl-3-(2-pyridyl)-2H,5H-1,3-oxazino(5,6-c)(1,2)benzothiazine-2,4(3H)dione-6,6-dioxideDTXCID90160526M01AC048-methyl-5-(pyridin-2-yl)-3-oxa-9??-thia-5,8-diazatricyclo(8.4.0.02,?)tetradeca-1(14),2(7),10,12-tetraene-4,6,9,9-tetrone5-Methyl-3-(pyridin-2-yl)benzo[5,6][1,2]thiazino[3,4-e][1,3]oxazine-2,4(3H,5H)-dione 6,6-dioxideDroxicam [INN]C16H11N3O5SE-3128
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Droxicam
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