Molecular Identity
primaquine diphosphate
4-N-(6-methoxyquinolin-8-yl)pentane-1,4-diamine;phosphoric acid
PubChem CID: 6135
Primaquine Phosphate is the phosphate salt form of primaquine, a synthetic, 8-aminoquinoline derivative with antimalarial properties. Although its mechanism of action is unclear, primaquine bind to and alter the properties of protozoal DNA. This agent eliminates tissue (exo-erythrocytic) malarial infection, preventing the development of the erythrocytic forms of the parasite which are responsible for relapses in Plasmodium vivax and ovale malaria. Primaquine is active against late hepatic stages (hypnozoites, schizonts).
2D Structure
Properties
C15H27N3O9P2
Molecular Formula
455.34
Molecular Weight
g/mol
455.1223
Exact Mass
Da
216
TPSA
May have limited oral absorption
8
H-Bond Donors
12
H-Bond Acceptors
312
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
primaquine diphosphate63-45-6PRIMAQUINE PHOSPHATEMalquine1,4-Pentanediamine, N4-(6-methoxy-8-quinolinyl)-, phosphate (1:2)Primaquini diphosphasCAMDENDTXSID6045248H0982HF78BNSC-149765WR 2975DTXCID4025248Diphosphate, PrimaquinePhosphate, PrimaquineRefChem:56453
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to primaquine diphosphate
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