Molecular Identity
prochlorperazine
2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine
PubChem CID: 4917
Prochlorperazine is a member of the class of phenothiazines that is 10H-phenothiazine having a chloro substituent at the 2-position and a 3-(4-methylpiperazin-1-yl)propyl group at the N-10 position. It has a role as a dopamine receptor D2 antagonist, an alpha-adrenergic antagonist, a dopaminergic antagonist, a cholinergic antagonist, an antiemetic, a first generation antipsychotic and an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor. It is an organochlorine compound, a member of phenothiazines, a N-alkylpiperazine and a N-methylpiperazine. It derives from a hydride of a 10H-phenothiazine.
2D Structure
Properties
C20H24ClN3S
Molecular Formula
373.90
Molecular Weight
g/mol
373.1379
Exact Mass
Da
4.9
XLogP
Drug-like (Lipinski: < 5)
35
TPSA
Good oral absorption (< 140 A²)
0
H-Bond Donors
4
H-Bond Acceptors
429
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
prochlorperazine58-38-8ProchlorperazinProchlorpromazineChlormeprazineChlorperazineProcloperazineCapazineProclorperazineMeterazineStemetilTementilKronocinComproEmelent
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to prochlorperazine
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