RMC-5552
[(1R,2R,4S)-2-methoxy-4-[(2R)-2-[(1R,9S,12S,14R,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,14,18-trihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,20-tetraoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]cyclohexyl] N-[2-[2-[2-[2-[2-[2-[2-[2-[3-[6-[[4-amino-3-(2-amino-1,3-benzoxazol-5-yl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
Molecular Identity
RMC-5552
[(1R,2R,4S)-2-methoxy-4-[(2R)-2-[(1R,9S,12S,14R,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,14,18-trihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,20-tetraoxo-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]cyclohexyl] N-[2-[2-[2-[2-[2-[2-[2-[2-[3-[6-[[4-amino-3-(2-amino-1,3-benzoxazol-5-yl)pyrazolo[3,4-d]pyrimidin-1-yl]methyl]-3,4-dihydro-1H-isoquinolin-2-yl]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
PubChem CID: 162640850
2D Structure
Properties
C93H136N10O24
Molecular Formula
1778.10
Molecular Weight
g/mol
1776.9729
Exact Mass
Da
7
XLogP
Above Lipinski threshold
433
TPSA
May have limited oral absorption
6
H-Bond Donors
30
H-Bond Acceptors
3460
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(16)
RMC-5552S6PL6DS4XK2382768-62-7RMC5552RefChem:1098142RMC 5552mTORC1 Kinase Inhibitor RMC-5552orb1694050CHEMBL5314926GTPL12338GLXC-26636BDBM50616044compound 38 [PMID: 36533617]HY-132168CS-0163553
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to RMC-5552
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