Rifaximin
[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,36-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22,30-octamethyl-6,23-dioxo-8,37-dioxa-24,27,33-triazahexacyclo[23.10.1.14,7.05,35.026,34.027,32]heptatriaconta-1(35),2,4,9,19,21,25(36),26(34),28,30,32-undecaen-13-yl] acetate
Molecular Identity
Rifaximin
[(7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,36-tetrahydroxy-11-methoxy-3,7,12,14,16,18,22,30-octamethyl-6,23-dioxo-8,37-dioxa-24,27,33-triazahexacyclo[23.10.1.14,7.05,35.026,34.027,32]heptatriaconta-1(35),2,4,9,19,21,25(36),26(34),28,30,32-undecaen-13-yl] acetate
PubChem CID: 6436173
Rifaximin is a semisynthetic member of the class of rifamycins and non-systemic gastrointestinal site-specific broad spectrum antibiotic. Used in the treatment of traveller's diarrhoea, hepatic encephalopathy and irritable bowel syndrome. It has a role as an antimicrobial agent, a gastrointestinal drug and an orphan drug. It is a lactam, a member of rifamycins, an acetate ester, a macrocycle, an organic heterohexacyclic compound, a cyclic ketal and a semisynthetic derivative.
2D Structure
Properties
C43H51N3O11
Molecular Formula
785.90
Molecular Weight
g/mol
785.3524
Exact Mass
Da
6.9
XLogP
Above Lipinski threshold
198
TPSA
May have limited oral absorption
5
H-Bond Donors
12
H-Bond Acceptors
1590
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
RifaximinRifaxidin80621-81-4RifacolXifaxanRifamycin L 105RifaximineRifaximinaNormixRifamycin L 105SVRifaximinumXifaxsanL-105XifaxantaL36O5T016N
Data from PubChem (NCBI)
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Trials and conditions connected to Rifaximin
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