Molecules/8-(4-((Dimethylamino)methyl)-2-methylphenyl)-5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)imidazo[1,2-c]pyrimidine-2-carbonitrile
8-(4-((Dimethylamino)methyl)-2-methylphenyl)-5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)imidazo[1,2-c]pyrimidine-2-carbonitrile
8-[4-[(dimethylamino)methyl]-2-methylphenyl]-5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]imidazo[1,2-c]pyrimidine-2-carbonitrile
Molecular Identity
8-(4-((Dimethylamino)methyl)-2-methylphenyl)-5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)imidazo[1,2-c]pyrimidine-2-carbonitrile
8-[4-[(dimethylamino)methyl]-2-methylphenyl]-5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]imidazo[1,2-c]pyrimidine-2-carbonitrile
PubChem CID: 155788096
2D Structure
Properties
C26H25FN6O
Molecular Formula
456.50
Molecular Weight
g/mol
456.2074
Exact Mass
Da
4.9
XLogP
Drug-like (Lipinski: < 5)
78.5
TPSA
Good oral absorption (< 140 A²)
1
H-Bond Donors
7
H-Bond Acceptors
744
Complexity
SMILES
Canonical SMILES
SMILES: CC1=C(C=CC(=C1)CN(C)C)C2=CN=C(N3C2=NC(=C3)C#N)NCC4=C(C=CC5=C4CCO5)FIsomeric SMILES
SMILES: CC1=C(C=CC(=C1)CN(C)C)C2=CN=C(N3C2=NC(=C3)C#N)NCC4=C(C=CC5=C4CCO5)FSynonyms(20)
ORIC-9442369769-29-7RinzimetostatMRTX-22198-(4-((dimethylamino)methyl)-2-methylphenyl)-5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)imidazo[1,2-c]pyrimidine-2-carbonitrileORIC944US11091495, Example 1738-[4-[(dimethylamino)methyl]-2-methylphenyl]-5-[(5-fluoro-2,3-dihydro-1-benzofuran-4-yl)methylamino]imidazo[1,2-c]pyrimidine-2-carbonitrileImidazo[1,2-c]pyrimidine-2-carbonitrile, 8-[4-[(dimethylamino)methyl]-2-methylphenyl]-5-[[(5-fluoro-2,3-dihydro-4-benzofuranyl)methyl]amino]-8-(4-((Dimethylamino)methyl)-2-methylphenyl)-5-[[[5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)imidazo[1,2-c]pyrimidine-2-carbonitrileIMIDAZO(1,2-C)PYRIMIDINE-2-CARBONITRILE, 8-(4-((DIMETHYLAMINO)METHYL)-2-METHYLPHENYL)-5-(((5-FLUORO-2,3-DIHYDRO-4-BENZOFURANYL)METHYL)AMINO)-rinzimetostat [INN]Rinzimetostat [WHO-DD]9X4NP88TGBMRTX2219
Data from PubChem (NCBI)
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Molecular Structure
8-(4-((Dimethylamino)methyl)-2-methylphenyl)-5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)imidazo[1,2-c]pyrimidine-2-carbonitrile
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Drug Network
Trials and conditions connected to 8-(4-((Dimethylamino)methyl)-2-methylphenyl)-5-(((5-fluoro-2,3-dihydrobenzofuran-4-yl)methyl)amino)imidazo[1,2-c]pyrimidine-2-carbonitrile
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