Ripretinib
1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea
Molecular Identity
Ripretinib
1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylurea
PubChem CID: 71584930
2D Structure
Properties
C24H21BrFN5O2
Molecular Formula
510.40
Molecular Weight
g/mol
509.0863
Exact Mass
Da
4.1
XLogP
Drug-like (Lipinski: < 5)
86.4
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
5
H-Bond Acceptors
746
Complexity
SMILES
Canonical SMILES
SMILES: CCN1C2=CC(=NC=C2C=C(C1=O)C3=CC(=C(C=C3Br)F)NC(=O)NC4=CC=CC=C4)NCIsomeric SMILES
SMILES: CCN1C2=CC(=NC=C2C=C(C1=O)C3=CC(=C(C=C3Br)F)NC(=O)NC4=CC=CC=C4)NCSynonyms(20)
Ripretinib1442472-39-0qinlockDCC26189XW757O13DDTXSID201027956KIT/PDGFR Inhibitor DCC-2618Urea, N-(4-bromo-5-(1-ethyl-1,2-dihydro-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl)-2-fluorophenyl)-N'-phenyl-1-[4-bromo-5-[1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl]-2-fluorophenyl]-3-phenylureaN-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,2-dihydro-1,6-naphthyridin-3-yl)-2-fluorophenyl)-N'-phenylurearipretinibum1-(4-bromo-5-(1-ethyl-7-(methylamino)-2-oxo-1,6-naphthyridin-3-yl)-2-fluorophenyl)-3-phenylureaRefChem:57787DTXCID1015135241-N'-(2,5-difluoro-4-(2-(1-methylpyrazol-4-yl)pyridin-4-yl)oxyphenyl)-1-N'-phenylcyclopropane-1,1-dicarboxamide
Data from PubChem (NCBI)
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