Molecules/Sacituzumab Govitecan

Sacituzumab Govitecan

(2R)-2-amino-3-[1-[[4-[[1-[2-[2-[2-[2-[2-[2-[2-[2-[2-[[2-[2-[[(2S)-6-amino-1-[4-[[(19S)-10,19-diethyl-7-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-19-yl]oxycarbonyloxymethyl]anilino]-1-oxohexan-2-yl]amino]-2-oxoethoxy]acetyl]amino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]triazol-4-yl]methylcarbamoyl]cyclohexyl]methyl]-2,5-dioxopyrrolidin-3-yl]sulfanylpropanoic acid

C76H104N12O24S1601.80 g/molCID 91668186

Compare

Molecular Identity

Sacituzumab Govitecan

PubChem CID: 91668186

2D Structure

Properties

C₇₆H₁₀₄N₁₂O₂₄S

Molecular Formula

1601.80

Molecular Weight

g/mol

1600.7007

Exact Mass

-3.3

XLogP

Drug-like (Lipinski: < 5)

497

TPSA

May have limited oral absorption

H-Bond Donors

H-Bond Acceptors

3150

Complexity

SMILES

Canonical SMILES

SMILES: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)OC(=O)OCC5=CC=C(C=C5)NC(=O)C(CCCCN)NC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN6C=C(N=N6)CNC(=O)C7CCC(CC7)CN8C(=O)CC(C8=O)SCC(C(=O)O)N)C2=NC9=C1C=C(C=C9)O

Isomeric SMILES

SMILES: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)[C@@]4(CC)OC(=O)OCC5=CC=C(C=C5)NC(=O)[C@H](CCCCN)NC(=O)COCC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCN6C=C(N=N6)CNC(=O)C7CCC(CC7)CN8C(=O)CC(C8=O)SC[C@@H](C(=O)O)N)C2=NC9=C1C=C(C=C9)O

Synonyms(20)

1491917-83-9hRS7-SN38IMMU-132TrodelvyM9BYU8XDQ6DTXSID401335985SacituzumabGovitecansacituzumabum govitecanumRefChem:58300Sacituzumab govitecan-hziyhRS7SN38RS7-SN38DTXCID601766057hRS7-SN38 Antibody Drug ConjugateHRS7-SN38-ANTIBODY-DRUG-CONJUGATE

Data from PubChem (NCBI)

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.

Molecular Structure

Sacituzumab Govitecan

Loading structure...

Source: PubChem

Drug Network

Trials and conditions connected to Sacituzumab Govitecan

Loading drug network...