baicalein
5,6,7-trihydroxy-2-phenylchromen-4-one
Molecular Identity
baicalein
5,6,7-trihydroxy-2-phenylchromen-4-one
PubChem CID: 5281605
Baicalein is a trihydroxyflavone with the hydroxy groups at positions C-5, -6 and -7. It has a role as an EC 4.1.1.17 (ornithine decarboxylase) inhibitor, an EC 3.4.22.69 (SARS coronavirus main proteinase) inhibitor, an anticoronaviral agent, a ferroptosis inhibitor, a geroprotector, an antioxidant, an antibacterial agent, an antineoplastic agent, an antifungal agent, an angiogenesis inhibitor, a radical scavenger, a hormone antagonist, a prostaglandin antagonist, an EC 1.13.11.31 (arachidonate 12-lipoxygenase) inhibitor, an EC 1.13.11.33 (arachidonate 15-lipoxygenase) inhibitor, an anti-inflammatory agent, an apoptosis inducer, an EC 3.4.21.26 (prolyl oligopeptidase) inhibitor and a plant metabolite. It is a conjugate acid of a baicalein(1-).
2D Structure
Properties
C15H10O5
Molecular Formula
270.24
Molecular Weight
g/mol
270.0528
Exact Mass
Da
1.7
XLogP
Drug-like (Lipinski: < 5)
87
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
5
H-Bond Acceptors
412
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
baicalein491-67-85,6,7-TrihydroxyflavoneNoroxylin5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one5,6,7-trihydroxy-2-phenylchromen-4-one5,6,7-Trihydroxy-2-phenyl-4H-1-benzopyran-4-oneNSC-661431CHEBI:2979DTXSID202238949QAH60606RefChem:5579DTXCID802389637-183-7MFCD00017459
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to baicalein
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