Tki258
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one;2-hydroxypropanoic acid;hydrate
Molecular Identity
Tki258
4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one;2-hydroxypropanoic acid;hydrate
PubChem CID: 135611162
2D Structure
Properties
C24H29FN6O5
Molecular Formula
500.50
Molecular Weight
g/mol
500.2183
Exact Mass
Da
149
TPSA
May have limited oral absorption
6
H-Bond Donors
10
H-Bond Acceptors
737
Complexity
SMILES
Canonical SMILES
SMILES: CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N.OIsomeric SMILES
SMILES: CC(C(=O)O)O.CN1CCN(CC1)C2=CC3=C(C=C2)N=C(N3)C4=C(C5=C(C=CC=C5F)NC4=O)N.OSynonyms(20)
TKI258TKI 258RefChem:135717915769-50-5Dovitinib lactateDovitinib Lactate Hydrate4-Amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate hydrateDovitinib lactate [USAN]UNII-69VKY8P7EA69VKY8P7EAChir 258Tki258 (hydrate)Chir-258 (hydrate)Dovitinib (lactate hydrate)Dovitinib lactate (USAN)
Data from PubChem (NCBI)
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