Tsn-084
N-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide
Molecular Identity
Tsn-084
N-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-2-oxo-6-propan-2-yloxypyridine-3-carboxamide
PubChem CID: 149276766
2D Structure
Properties
C32H26F2N6O4
Molecular Formula
596.60
Molecular Weight
g/mol
596.1984
Exact Mass
Da
5.3
XLogP
Above Lipinski threshold
114
TPSA
Good oral absorption (< 140 A²)
2
H-Bond Donors
8
H-Bond Acceptors
1110
Complexity
SMILES
Canonical SMILES
SMILES: CC(C)OC1=CC=C(C(=O)N1C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C=C5C(=C4)C=NN5C)C6=CNN=C6)FIsomeric SMILES
SMILES: CC(C)OC1=CC=C(C(=O)N1C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C=C5C(=C4)C=NN5C)C6=CNN=C6)FSynonyms(20)
TSN-084TSN0849FJ3MBL7XW2412309-60-33-PYRIDINECARBOXAMIDE, N-(3-FLUORO-4-((1-METHYL-6-(1H-PYRAZOL-4-YL)-1H-INDAZOL-5-YL)OXY)PHENYL)-1-(4-FLUOROPHENYL)-1,2-DIHYDRO-6-(1-METHYLETHOXY)-2-OXO-N-(3-fluoro-4-((1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl)oxy)phenyl)-1-(4-fluorophenyl)-1,2-dihydro-6-(1-methylethoxy)-2-oxo-3-pyridinecarboxamideN-[3-fluoro-4-[[1-methyl-6-(1H-pyrazol-4-yl)-1H-indazol-5-yl]oxy]phenyl]-1-(4-fluorophenyl)-1,2-dihydro-6-(1-methylethoxy)-2-oxo-3-pyridinecarboxamideRefChem:1100585TSN 084Protein Kinase Inhibitor TSN084Multiple Kinase Inhibitor TSN084c-Met/FLT3/TRK/CDK8/19 Inhibitor TSN084TRK-IN-25orb2565121CHEMBL5314969
Data from PubChem (NCBI)
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Drug Network
Trials and conditions connected to Tsn-084
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