Telbivudine
1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
Molecular Identity
Telbivudine
1-[(2S,4R,5S)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-methylpyrimidine-2,4-dione
PubChem CID: 159269
Telbivudine is a pyrimidine 2'-deoxyribonucleoside that is the L-enantiomer of thymine. A synthetic thymidine nucleoside analogue with activity against HBV DNA polymerase. It has a role as an antiviral drug and an EC 2.7.7.49 (RNA-directed DNA polymerase) inhibitor. It is functionally related to a thymine. It is an enantiomer of a thymidine.
2D Structure
Properties
C10H14N2O5
Molecular Formula
242.23
Molecular Weight
g/mol
242.0903
Exact Mass
Da
-1.2
XLogP
Drug-like (Lipinski: < 5)
99.1
TPSA
Good oral absorption (< 140 A²)
3
H-Bond Donors
5
H-Bond Acceptors
381
Complexity
SMILES
Canonical SMILES
SMILES: Synonyms(20)
Telbivudine3424-98-42'-Deoxy-L-thymidineEpavudineTyzekaL-ThymidineTelbivudinbeta-L-ThymidineL-DeoxythymidineSebivoNV-02Bbeta-L-2'-DeoxythymidineLDT600LDT-600Telbivudina
Data from PubChem (NCBI)
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Drug Network
Trials and conditions connected to Telbivudine
Loading drug network...